L827-1597 Screening compound: N-benzyl-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-methylpyridin-2-amine

L827-1597 Screening compound: N-benzyl-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-methylpyridin-2-amine
L827-1597 Screening compound: N-benzyl-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-methylpyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-1597
N-benzyl-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-methylpyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-1597

Molecular Formula

C21H17FN4O (C21 H17 FN4 O)

Compound Name

N-benzyl-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-methylpyridin-2-amine

IUPAC name

N-benzyl-5-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-N-methylpyridin-2-amine

SMILES

CN(Cc1ccccc1)c(cc1)ncc1-c1nc(-c2cccc(F)c2)no1

InChI

InChI=1S/C21H17FN4O/c1-26(14-15-6-3-2-4-7-15)19-11-10-17(13-23-19)21-24-20(25-27-21)16-8-5-9-18(22)12-16/h2-13H,14H2,1H3

InChI Key

LVQDNCAOKRZRQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478321

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.380

Distribution Coefficient, logD

5.345

Water Solubility, LogSw

-5.45

Polar Surface Area

43.200

Acid Dissociation Constant (pKa)

23.29

Base Dissociation Constant (pKb)

6.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

L827-1597 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L827-1597 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-1597?
Check Price and Availability of L827-1597, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-1597 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-1597
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-1597
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-1597 available by request