L827-1634 Screening compound: 5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine

L827-1634 Screening compound: 5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
L827-1634 Screening compound: 5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-1634
5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-1634

Molecular Formula

C21H17FN4O2 (C21 H17 FN4 O2)

Compound Name

5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine

IUPAC name

5-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine

SMILES

COc1ccc(CNc(cc2)ncc2-c2nc(-c3cccc(F)c3)no2)cc1

InChI

InChI=1S/C21H17FN4O2/c1-27-18-8-5-14(6-9-18)12-23-19-10-7-16(13-24-19)21-25-20(26-28-21)15-3-2-4-17(22)11-15/h2-11,13H,12H2,1H3,(H,23,24)

InChI Key

MXYWRXQGKDOMJF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478332

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.907

Distribution Coefficient, logD

4.872

Water Solubility, LogSw

-4.57

Polar Surface Area

59.127

Acid Dissociation Constant (pKa)

19.49

Base Dissociation Constant (pKb)

6.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

L827-1634 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L827-1634 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-1634?
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What is the minimum amount of L827-1634 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-1634
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-1634
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-1634 available by request