L827-2020 Screening compound: 5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine

L827-2020 Screening compound: 5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine
L827-2020 Screening compound: 5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-2020
5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-2020

Molecular Formula

C19H15FN4O2 (C19 H15 FN4 O2)

Compound Name

5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine

IUPAC name

5-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]-N-[(5-methylfuran-2-yl)methyl]pyridin-2-amine

SMILES

Cc1ccc(CNc(cc2)ncc2-c2nc(-c(cc3)ccc3F)no2)o1

InChI

InChI=1S/C19H15FN4O2/c1-12-2-8-16(25-12)11-22-17-9-5-14(10-21-17)19-23-18(24-26-19)13-3-6-15(20)7-4-13/h2-10H,11H2,1H3,(H,21,22)

InChI Key

NECPBMTWBITDDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478422

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.891

Distribution Coefficient, logD

4.868

Water Solubility, LogSw

-4.50

Polar Surface Area

58.846

Acid Dissociation Constant (pKa)

18.31

Base Dissociation Constant (pKb)

6.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

L827-2020 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L827-2020 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-2020?
Check Price and Availability of L827-2020, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-2020 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-2020
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-2020
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-2020 available by request