L827-2177 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

L827-2177 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine
L827-2177 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-2177
N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-2177

Molecular Formula

C23H28FN5O (C23 H28 FN5 O)

Compound Name

N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

IUPAC name

N-[3-(azepan-1-yl)butyl]-5-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]pyridin-2-amine

SMILES

CC(CCNc(cc1)ncc1-c1nc(-c(cc2)ccc2F)no1)N1CCCCCC1

InChI

InChI=1S/C23H28FN5O/c1-17(29-14-4-2-3-5-15-29)12-13-25-21-11-8-19(16-26-21)23-27-22(28-30-23)18-6-9-20(24)10-7-18/h6-11,16-17H,2-5,12-15H2,1H3,(H,25,26)/t17-/m0/s1

InChI Key

OUECABLYBPDWSC-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27478434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.155

Distribution Coefficient, logD

2.703

Water Solubility, LogSw

-4.82

Polar Surface Area

55.396

Acid Dissociation Constant (pKa)

20.34

Base Dissociation Constant (pKb)

9.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

L827-2177 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L827-2177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-2177?
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What is the minimum amount of L827-2177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-2177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-2177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-2177 available by request