L829-0375 Screening compound: 4-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(3,4-dimethylphenyl)pyrrolidin-2-one

L829-0375 Screening compound: 4-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(3,4-dimethylphenyl)pyrrolidin-2-one
L829-0375 Screening compound: 4-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(3,4-dimethylphenyl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L829-0375
4-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(3,4-dimethylphenyl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L829-0375

Molecular Formula

C26H24N4O2S (C26 H24 N4 O2 S)

Compound Name

4-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(3,4-dimethylphenyl)pyrrolidin-2-one

IUPAC name

4-{3-[3-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}-1-(34-dimethylphenyl)pyrrolidin-2-one

SMILES

Cc(cc1)c(C)cc1N(CC(C1)c2nc(-c3cccc(-c4csc(C5CC5)n4)c3)no2)C1=O

InChI

InChI=1S/C26H24N4O2S/c1-15-6-9-21(10-16(15)2)30-13-20(12-23(30)31)25-28-24(29-32-25)19-5-3-4-18(11-19)22-14-33-26(27-22)17-7-8-17/h3-6,9-11,14,17,20H,7-8,12-13H2,1-2H3/t20-/m0/s1

InChI Key

PHOXKTKEJIXKER-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27478719

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.743

Distribution Coefficient, logD

6.742

Water Solubility, LogSw

-5.63

Polar Surface Area

58.380

Acid Dissociation Constant (pKa)

11.87

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.80

L829-0375 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L829-0375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L829-0375?
Check Price and Availability of L829-0375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L829-0375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L829-0375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L829-0375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L829-0375 available by request