L829-0392 Screening compound: 3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazole

L829-0392 Screening compound: 3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazole
L829-0392 Screening compound: 3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L829-0392
3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L829-0392

Molecular Formula

C23H21N3O3S2 (C23 H21 N3 O3 S2)

Compound Name

3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-1,2,4-oxadiazole

IUPAC name

3-[3-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-5-[2-(4-methylbenzenesulfonyl)ethyl]-124-oxadiazole

SMILES

Cc(cc1)ccc1S(CCc1nc(-c2cc(-c3csc(C4CC4)n3)ccc2)no1)(=O)=O

InChI

InChI=1S/C23H21N3O3S2/c1-15-5-9-19(10-6-15)31(27,28)12-11-21-25-22(26-29-21)18-4-2-3-17(13-18)20-14-30-23(24-20)16-7-8-16/h2-6,9-10,13-14,16H,7-8,11-12H2,1H3

InChI Key

SIWKKLDLNBJENI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478727

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.611

Distribution Coefficient, logD

5.611

Water Solubility, LogSw

-5.59

Polar Surface Area

70.332

Acid Dissociation Constant (pKa)

20.92

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

L829-0392 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L829-0392 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L829-0392?
Check Price and Availability of L829-0392, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L829-0392 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L829-0392
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L829-0392
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L829-0392 available by request