L829-0424 Screening compound: 2-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrazine

L829-0424 Screening compound: 2-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrazine
L829-0424 Screening compound: 2-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L829-0424
2-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L829-0424

Molecular Formula

C18H13N5OS (C18 H13 N5 OS)

Compound Name

2-{3-[3-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrazine

IUPAC name

2-{3-[3-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}pyrazine

SMILES

C(C1)C1c1nc(-c2cc(-c3noc(-c4nccnc4)n3)ccc2)cs1

InChI

InChI=1S/C18H13N5OS/c1-2-12(15-10-25-18(21-15)11-4-5-11)8-13(3-1)16-22-17(24-23-16)14-9-19-6-7-20-14/h1-3,6-11H,4-5H2

InChI Key

QEUWJLMVEZVBCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478738

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.018

Distribution Coefficient, logD

4.018

Water Solubility, LogSw

-4.15

Polar Surface Area

60.195

Acid Dissociation Constant (pKa)

23.73

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L829-0424 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L829-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L829-0424?
Check Price and Availability of L829-0424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L829-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L829-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L829-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L829-0424 available by request