L839-0112 Screening compound: 1-methyl-4-{[4-(5-methyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine

L839-0112 Screening compound: 1-methyl-4-{[4-(5-methyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine
L839-0112 Screening compound: 1-methyl-4-{[4-(5-methyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L839-0112
1-methyl-4-{[4-(5-methyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L839-0112

Molecular Formula

C12H16N4O3S2 (C12 H16 N4 O3 S2)

Compound Name

1-methyl-4-{[4-(5-methyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine

IUPAC name

1-methyl-4-{[4-(5-methyl-134-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}piperazine

SMILES

Cc1nnc(-c2csc(S(N3CCN(C)CC3)(=O)=O)c2)o1

InChI

InChI=1S/C12H16N4O3S2/c1-9-13-14-12(19-9)10-7-11(20-8-10)21(17,18)16-5-3-15(2)4-6-16/h7-8H,3-6H2,1-2H3

InChI Key

CLVNFPKAZUULTQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27479091

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.514

Distribution Coefficient, logD

0.425

Water Solubility, LogSw

-1.57

Polar Surface Area

66.188

Acid Dissociation Constant (pKa)

28.52

Base Dissociation Constant (pKb)

6.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L839-0112 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L839-0112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L839-0112?
Check Price and Availability of L839-0112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L839-0112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L839-0112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L839-0112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L839-0112 available by request