L839-1655 Screening compound: 2-{[4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

L839-1655 Screening compound: 2-{[4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline
L839-1655 Screening compound: 2-{[4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L839-1655
2-{[4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L839-1655

Molecular Formula

C18H17N3O3S2 (C18 H17 N3 O3 S2)

Compound Name

2-{[4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{[4-(5-cyclopropyl-134-oxadiazol-2-yl)thiophen-2-yl]sulfonyl}-1234-tetrahydroisoquinoline

SMILES

O=S(c1cc(-c2nnc(C3CC3)o2)cs1)(N(CC1)Cc2c1cccc2)=O

InChI

InChI=1S/C18H17N3O3S2/c22-26(23,21-8-7-12-3-1-2-4-14(12)10-21)16-9-15(11-25-16)18-20-19-17(24-18)13-5-6-13/h1-4,9,11,13H,5-8,10H2

InChI Key

XMAUILCTDVRVES-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27479201

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.650

Distribution Coefficient, logD

3.650

Water Solubility, LogSw

-3.94

Polar Surface Area

63.397

Acid Dissociation Constant (pKa)

24.36

Base Dissociation Constant (pKb)

-0.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L839-1655 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L839-1655 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L839-1655?
Check Price and Availability of L839-1655, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L839-1655 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L839-1655
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L839-1655
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L839-1655 available by request