L839-1666 Screening compound: 4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide

L839-1666 Screening compound: 4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide
L839-1666 Screening compound: 4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L839-1666
4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L839-1666

Molecular Formula

C12H15N3O3S2 (C12 H15 N3 O3 S2)

Compound Name

4-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide

IUPAC name

4-(5-cyclopropyl-134-oxadiazol-2-yl)-N-(propan-2-yl)thiophene-2-sulfonamide

SMILES

CC(C)NS(c1cc(-c2nnc(C3CC3)o2)cs1)(=O)=O

InChI

InChI=1S/C12H15N3O3S2/c1-7(2)15-20(16,17)10-5-9(6-19-10)12-14-13-11(18-12)8-3-4-8/h5-8,15H,3-4H2,1-2H3

InChI Key

NUQVMNVUJWFGQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27479206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

313.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.336

Distribution Coefficient, logD

2.336

Water Solubility, LogSw

-2.58

Polar Surface Area

73.242

Acid Dissociation Constant (pKa)

10.22

Base Dissociation Constant (pKb)

-0.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L839-1666 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L839-1666 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L839-1666?
Check Price and Availability of L839-1666, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L839-1666 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L839-1666
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L839-1666
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L839-1666 available by request