L840-0106 Screening compound: N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-1,3,4-oxadiazol-2-yl]thiophene-2-sulfonamide

L840-0106 Screening compound: N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-1,3,4-oxadiazol-2-yl]thiophene-2-sulfonamide
L840-0106 Screening compound: N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-1,3,4-oxadiazol-2-yl]thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L840-0106
N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-1,3,4-oxadiazol-2-yl]thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L840-0106

Molecular Formula

C14H16N4O4S2 (C14 H16 N4 O4 S2)

Compound Name

N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-1,3,4-oxadiazol-2-yl]thiophene-2-sulfonamide

IUPAC name

N-cyclopropyl-4-[5-(pyrrolidine-1-carbonyl)-134-oxadiazol-2-yl]thiophene-2-sulfonamide

SMILES

O=C(c1nnc(-c2csc(S(NC3CC3)(=O)=O)c2)o1)N1CCCC1

InChI

InChI=1S/C14H16N4O4S2/c19-14(18-5-1-2-6-18)13-16-15-12(22-13)9-7-11(23-8-9)24(20,21)17-10-3-4-10/h7-8,10,17H,1-6H2

InChI Key

PLDGJWMDZVMHFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27479289

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.135

Distribution Coefficient, logD

1.134

Water Solubility, LogSw

-2.24

Polar Surface Area

90.815

Acid Dissociation Constant (pKa)

10.22

Base Dissociation Constant (pKb)

-4.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L840-0106 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Angiogenesis library (14822 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L840-0106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L840-0106?
Check Price and Availability of L840-0106, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L840-0106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L840-0106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L840-0106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L840-0106 available by request