L849-1430 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethan-1-one

L849-1430 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethan-1-one
L849-1430 Screening compound: 1-(2,3-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L849-1430
1-(2,3-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L849-1430

Molecular Formula

C24H24N6OS (C24 H24 N6 OS)

Compound Name

1-(2,3-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethan-1-one

IUPAC name

1-(23-dihydro-1H-indol-1-yl)-2-({4-methyl-5-[1-methyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-4H-124-triazol-3-yl}sulfanyl)ethan-1-one

SMILES

Cc(cc1)ccc1-c1nn(C)cc1-c(n1C)nnc1SCC(N(CC1)c2c1cccc2)=O

InChI

InChI=1S/C24H24N6OS/c1-16-8-10-18(11-9-16)22-19(14-28(2)27-22)23-25-26-24(29(23)3)32-15-21(31)30-13-12-17-6-4-5-7-20(17)30/h4-11,14H,12-13,15H2,1-3H3

InChI Key

GVQXKVRSBJUVNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27479720

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.360

Distribution Coefficient, logD

3.360

Water Solubility, LogSw

-3.52

Polar Surface Area

55.558

Acid Dissociation Constant (pKa)

18.39

Base Dissociation Constant (pKb)

1.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L849-1430 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L849-1430 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L849-1430?
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What is the minimum amount of L849-1430 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L849-1430
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L849-1430
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L849-1430 available by request