L851-0437 Screening compound: 5-[5-(2-fluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-methyl-1,2,4-oxadiazole

L851-0437 Screening compound: 5-[5-(2-fluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-methyl-1,2,4-oxadiazole
L851-0437 Screening compound: 5-[5-(2-fluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-methyl-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-0437
5-[5-(2-fluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-methyl-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-0437

Molecular Formula

C17H16FN5O2 (C17 H16 FN5 O2)

Compound Name

5-[5-(2-fluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-methyl-1,2,4-oxadiazole

IUPAC name

5-[5-(2-fluorobenzoyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]-3-methyl-124-oxadiazole

SMILES

Cc1noc(-c2nn(C)c(CC3)c2CN3C(c(cccc2)c2F)=O)n1

InChI

InChI=1S/C17H16FN5O2/c1-10-19-16(25-21-10)15-12-9-23(8-7-14(12)22(2)20-15)17(24)11-5-3-4-6-13(11)18/h3-6H,7-9H2,1-2H3

InChI Key

ALPWVBVCAFQLJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119960

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.114

Distribution Coefficient, logD

1.114

Water Solubility, LogSw

-2.26

Polar Surface Area

62.856

Acid Dissociation Constant (pKa)

21.01

Base Dissociation Constant (pKb)

-0.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L851-0437 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-0437?
Check Price and Availability of L851-0437, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-0437 available by request