L851-0845 Screening compound: 3-CYCLOPROPYL-5-[1-METHYL-5-(1-PHENYLCYCLOPROPANECARBONYL)-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

L851-0845 Screening compound: 3-CYCLOPROPYL-5-[1-METHYL-5-(1-PHENYLCYCLOPROPANECARBONYL)-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE
L851-0845 Screening compound: 3-CYCLOPROPYL-5-[1-METHYL-5-(1-PHENYLCYCLOPROPANECARBONYL)-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-0845
3-CYCLOPROPYL-5-[1-METHYL-5-(1-PHENYLCYCLOPROPANECARBONYL)-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-0845

Molecular Formula

C22H23N5O2 (C22 H23 N5 O2)

Compound Name

3-CYCLOPROPYL-5-[1-METHYL-5-(1-PHENYLCYCLOPROPANECARBONYL)-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

IUPAC name

n/a

SMILES

Cn(c(CC1)c2CN1C(C1(CC1)c1ccccc1)=O)nc2-c1nc(C2CC2)no1

InChI

InChI=1S/C22H23N5O2/c1-26-17-9-12-27(21(28)22(10-11-22)15-5-3-2-4-6-15)13-16(17)18(24-26)20-23-19(25-29-20)14-7-8-14/h2-6,14H,7-13H2,1H3

InChI Key

GNXLCKMGDOVJHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119987

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.540

Distribution Coefficient, logD

2.540

Water Solubility, LogSw

-2.43

Polar Surface Area

63.747

Acid Dissociation Constant (pKa)

21.04

Base Dissociation Constant (pKb)

7.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

L851-0845 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Immune system
  • animal
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-0845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-0845?
Check Price and Availability of L851-0845, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-0845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-0845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-0845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-0845 available by request