L851-1333 Screening compound: 5-[5-(2-ethoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-(2-fluorophenyl)-1,2,4-oxadiazole

L851-1333 Screening compound: 5-[5-(2-ethoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-(2-fluorophenyl)-1,2,4-oxadiazole
L851-1333 Screening compound: 5-[5-(2-ethoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-(2-fluorophenyl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-1333
5-[5-(2-ethoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-(2-fluorophenyl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-1333

Molecular Formula

C24H22FN5O3 (C24 H22 FN5 O3)

Compound Name

5-[5-(2-ethoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-3-(2-fluorophenyl)-1,2,4-oxadiazole

IUPAC name

5-[5-(2-ethoxybenzoyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]-3-(2-fluorophenyl)-124-oxadiazole

SMILES

CCOc(cccc1)c1C(N(CC1)Cc2c1n(C)nc2-c1nc(-c(cccc2)c2F)no1)=O

InChI

InChI=1S/C24H22FN5O3/c1-3-32-20-11-7-5-9-16(20)24(31)30-13-12-19-17(14-30)21(27-29(19)2)23-26-22(28-33-23)15-8-4-6-10-18(15)25/h4-11H,3,12-14H2,1-2H3

InChI Key

VCUZALBQAGWGBJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28120021

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.143

Distribution Coefficient, logD

3.143

Water Solubility, LogSw

-3.44

Polar Surface Area

70.182

Acid Dissociation Constant (pKa)

21.25

Base Dissociation Constant (pKb)

-1.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L851-1333 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-1333 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-1333?
Check Price and Availability of L851-1333, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-1333 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-1333
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-1333
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-1333 available by request