L851-1350 Screening compound: 1-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenylbutan-1-one

L851-1350 Screening compound: 1-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenylbutan-1-one
L851-1350 Screening compound: 1-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenylbutan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-1350
1-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenylbutan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-1350

Molecular Formula

C25H24FN5O2 (C25 H24 FN5 O2)

Compound Name

1-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenylbutan-1-one

IUPAC name

1-{3-[3-(2-fluorophenyl)-124-oxadiazol-5-yl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl}-2-phenylbutan-1-one

SMILES

CCC(C(N(CC1)Cc2c1n(C)nc2-c1nc(-c(cccc2)c2F)no1)=O)c1ccccc1

InChI

InChI=1S/C25H24FN5O2/c1-3-17(16-9-5-4-6-10-16)25(32)31-14-13-21-19(15-31)22(28-30(21)2)24-27-23(29-33-24)18-11-7-8-12-20(18)26/h4-12,17H,3,13-15H2,1-2H3/t17-/m1/s1

InChI Key

PFXORGPUZIHLSS-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD28120024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.996

Distribution Coefficient, logD

3.996

Water Solubility, LogSw

-4.33

Polar Surface Area

62.972

Acid Dissociation Constant (pKa)

17.90

Base Dissociation Constant (pKb)

0.62

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.00

L851-1350 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L851-1350 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-1350?
Check Price and Availability of L851-1350, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-1350 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-1350
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-1350
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-1350 available by request