L851-1382 Screening compound: 4-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl}benzonitrile

L851-1382 Screening compound: 4-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl}benzonitrile
L851-1382 Screening compound: 4-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl}benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-1382
4-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl}benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-1382

Molecular Formula

C23H17FN6O2 (C23 H17 FN6 O2)

Compound Name

4-{3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl}benzonitrile

IUPAC name

4-{3-[3-(2-fluorophenyl)-124-oxadiazol-5-yl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-5-carbonyl}benzonitrile

SMILES

Cn(c(CC1)c2CN1C(c(cc1)ccc1C#N)=O)nc2-c1nc(-c(cccc2)c2F)no1

InChI

InChI=1S/C23H17FN6O2/c1-29-19-10-11-30(23(31)15-8-6-14(12-25)7-9-15)13-17(19)20(27-29)22-26-21(28-32-22)16-4-2-3-5-18(16)24/h2-9H,10-11,13H2,1H3

InChI Key

AERCQJLNIRROJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.461

Distribution Coefficient, logD

2.461

Water Solubility, LogSw

-2.81

Polar Surface Area

80.028

Acid Dissociation Constant (pKa)

21.25

Base Dissociation Constant (pKb)

-1.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L851-1382 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-1382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-1382?
Check Price and Availability of L851-1382, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-1382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-1382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-1382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-1382 available by request