L851-1443 Screening compound: 3-BENZYL-5-[5-(2-ETHOXYBENZOYL)-1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

L851-1443 Screening compound: 3-BENZYL-5-[5-(2-ETHOXYBENZOYL)-1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE
L851-1443 Screening compound: 3-BENZYL-5-[5-(2-ETHOXYBENZOYL)-1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-1443
3-BENZYL-5-[5-(2-ETHOXYBENZOYL)-1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-1443

Molecular Formula

C25H25N5O3 (C25 H25 N5 O3)

Compound Name

3-BENZYL-5-[5-(2-ETHOXYBENZOYL)-1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[4,3-C]PYRIDIN-3-YL]-1,2,4-OXADIAZOLE

IUPAC name

n/a

SMILES

CCOc(cccc1)c1C(N(CC1)Cc2c1n(C)nc2-c1nc(Cc2ccccc2)no1)=O

InChI

InChI=1S/C25H25N5O3/c1-3-32-21-12-8-7-11-18(21)25(31)30-14-13-20-19(16-30)23(27-29(20)2)24-26-22(28-33-24)15-17-9-5-4-6-10-17/h4-12H,3,13-16H2,1-2H3

InChI Key

HACLKEMSUYKAIT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28120049

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.020

Distribution Coefficient, logD

3.020

Water Solubility, LogSw

-3.46

Polar Surface Area

71.173

Acid Dissociation Constant (pKa)

21.25

Base Dissociation Constant (pKb)

-0.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

L851-1443 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-1443 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-1443?
Check Price and Availability of L851-1443, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-1443 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-1443
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-1443
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-1443 available by request