L851-2087 Screening compound: 1-[1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one

L851-2087 Screening compound: 1-[1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one
L851-2087 Screening compound: 1-[1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-2087
1-[1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-2087

Molecular Formula

C16H17N5O2S (C16 H17 N5 O2 S)

Compound Name

1-[1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one

IUPAC name

1-[1-methyl-3-(3-methyl-124-oxadiazol-5-yl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-2-(thiophen-3-yl)ethan-1-one

SMILES

Cc1noc(-c2nn(C)c(CC3)c2CN3C(Cc2cscc2)=O)n1

InChI

InChI=1S/C16H17N5O2S/c1-10-17-16(23-19-10)15-12-8-21(5-3-13(12)20(2)18-15)14(22)7-11-4-6-24-9-11/h4,6,9H,3,5,7-8H2,1-2H3

InChI Key

LOCBPABTTJEWGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28120086

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.098

Distribution Coefficient, logD

1.098

Water Solubility, LogSw

-2.12

Polar Surface Area

63.347

Acid Dissociation Constant (pKa)

18.22

Base Dissociation Constant (pKb)

0.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L851-2087 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-2087 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-2087?
Check Price and Availability of L851-2087, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-2087 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-2087
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-2087
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-2087 available by request