L851-2733 Screening compound: 1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one

L851-2733 Screening compound: 1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one
L851-2733 Screening compound: 1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L851-2733
1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L851-2733

Molecular Formula

C22H19FN6O2 (C22 H19 FN6 O2)

Compound Name

1-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one

IUPAC name

1-{3-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl}-2-(pyridin-3-yl)ethan-1-one

SMILES

Cn(c(CC1)c2CN1C(Cc1cnccc1)=O)nc2-c1nc(-c2cccc(F)c2)no1

InChI

InChI=1S/C22H19FN6O2/c1-28-18-7-9-29(19(30)10-14-4-3-8-24-12-14)13-17(18)20(26-28)22-25-21(27-31-22)15-5-2-6-16(23)11-15/h2-6,8,11-12H,7,9-10,13H2,1H3

InChI Key

UBHNDFVTCXTFJH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480416

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.301

Distribution Coefficient, logD

2.293

Water Solubility, LogSw

-2.27

Polar Surface Area

71.963

Acid Dissociation Constant (pKa)

14.50

Base Dissociation Constant (pKb)

5.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L851-2733 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Proteases
  • GPCR
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L851-2733 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L851-2733?
Check Price and Availability of L851-2733, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L851-2733 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L851-2733
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L851-2733
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L851-2733 available by request