L854-0753 Screening compound: 2-(2-chlorophenyl)-5-[5-(3,4-difluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-1,3,4-oxadiazole

L854-0753 Screening compound: 2-(2-chlorophenyl)-5-[5-(3,4-difluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-1,3,4-oxadiazole
L854-0753 Screening compound: 2-(2-chlorophenyl)-5-[5-(3,4-difluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L854-0753
2-(2-chlorophenyl)-5-[5-(3,4-difluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L854-0753

Molecular Formula

C22H16ClF2N5O2 (C22 H16 ClF2 N5 O2)

Compound Name

2-(2-chlorophenyl)-5-[5-(3,4-difluorobenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-1,3,4-oxadiazole

IUPAC name

2-(2-chlorophenyl)-5-[5-(34-difluorobenzoyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]-134-oxadiazole

SMILES

Cn(c(CC1)c2CN1C(c(cc1)cc(F)c1F)=O)nc2-c1nnc(-c(cccc2)c2Cl)o1

InChI

InChI=1S/C22H16ClF2N5O2/c1-29-18-8-9-30(22(31)12-6-7-16(24)17(25)10-12)11-14(18)19(28-29)21-27-26-20(32-21)13-4-2-3-5-15(13)23/h2-7,10H,8-9,11H2,1H3

InChI Key

ZFPDZBIWSYZMRI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480637

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.919

Distribution Coefficient, logD

2.919

Water Solubility, LogSw

-3.72

Polar Surface Area

61.810

Acid Dissociation Constant (pKa)

20.86

Base Dissociation Constant (pKb)

-1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L854-0753 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GABA Library (7115 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L854-0753 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L854-0753?
Check Price and Availability of L854-0753, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L854-0753 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L854-0753
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L854-0753
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L854-0753 available by request