L854-0795 Screening compound: 1-{3-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenoxyethan-1-one

L854-0795 Screening compound: 1-{3-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenoxyethan-1-one
L854-0795 Screening compound: 1-{3-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenoxyethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L854-0795
1-{3-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenoxyethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L854-0795

Molecular Formula

C23H20ClN5O3 (C23 H20 ClN5 O3)

Compound Name

1-{3-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-2-phenoxyethan-1-one

IUPAC name

1-{3-[5-(2-chlorophenyl)-134-oxadiazol-2-yl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl}-2-phenoxyethan-1-one

SMILES

Cn(c(CC1)c2CN1C(COc1ccccc1)=O)nc2-c1nnc(-c(cccc2)c2Cl)o1

InChI

InChI=1S/C23H20ClN5O3/c1-28-19-11-12-29(20(30)14-31-15-7-3-2-4-8-15)13-17(19)21(27-28)23-26-25-22(32-23)16-9-5-6-10-18(16)24/h2-10H,11-14H2,1H3

InChI Key

JIVGUGCQQRSQKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15135200

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.9

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.468

Distribution Coefficient, logD

2.468

Water Solubility, LogSw

-3.22

Polar Surface Area

68.782

Acid Dissociation Constant (pKa)

22.24

Base Dissociation Constant (pKb)

7.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L854-0795 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L854-0795 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L854-0795?
Check Price and Availability of L854-0795, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L854-0795 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L854-0795
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L854-0795
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L854-0795 available by request