L856-0041 Screening compound: 2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-(4-fluorophenyl)-1,3,4-oxadiazole

L856-0041 Screening compound: 2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-(4-fluorophenyl)-1,3,4-oxadiazole
L856-0041 Screening compound: 2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-(4-fluorophenyl)-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L856-0041
2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-(4-fluorophenyl)-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L856-0041

Molecular Formula

C19H15ClFN5O3S2 (C19 H15 ClFN5 O3 S2)

Compound Name

2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-(4-fluorophenyl)-1,3,4-oxadiazole

IUPAC name

2-{5-[(5-chlorothiophen-2-yl)sulfonyl]-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl}-5-(4-fluorophenyl)-134-oxadiazole

SMILES

Cn(c(CC1)c2CN1S(c(s1)ccc1Cl)(=O)=O)nc2-c1nnc(-c(cc2)ccc2F)o1

InChI

InChI=1S/C19H15ClFN5O3S2/c1-25-14-8-9-26(31(27,28)16-7-6-15(20)30-16)10-13(14)17(24-25)19-23-22-18(29-19)11-2-4-12(21)5-3-11/h2-7H,8-10H2,1H3

InChI Key

LCDHSGKEPCANDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480702

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.94

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.133

Distribution Coefficient, logD

3.133

Water Solubility, LogSw

-3.63

Polar Surface Area

77.891

Acid Dissociation Constant (pKa)

21.92

Base Dissociation Constant (pKb)

-2.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

L856-0041 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Agro:
  • Agro
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L856-0041 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L856-0041?
Check Price and Availability of L856-0041, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L856-0041 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L856-0041
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L856-0041
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L856-0041 available by request