L856-0046 Screening compound: 2-(4-fluorophenyl)-5-{1-methyl-5-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-1,3,4-oxadiazole

L856-0046 Screening compound: 2-(4-fluorophenyl)-5-{1-methyl-5-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-1,3,4-oxadiazole
L856-0046 Screening compound: 2-(4-fluorophenyl)-5-{1-methyl-5-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L856-0046
2-(4-fluorophenyl)-5-{1-methyl-5-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L856-0046

Molecular Formula

C21H22FN7O3S (C21 H22 FN7 O3 S)

Compound Name

2-(4-fluorophenyl)-5-{1-methyl-5-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-1,3,4-oxadiazole

IUPAC name

2-(4-fluorophenyl)-5-{1-methyl-5-[(135-trimethyl-1H-pyrazol-4-yl)sulfonyl]-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl}-134-oxadiazole

SMILES

Cc(n(C)nc1C)c1S(N(CC1)Cc2c1n(C)nc2-c1nnc(-c(cc2)ccc2F)o1)(=O)=O

InChI

InChI=1S/C21H22FN7O3S/c1-12-19(13(2)27(3)25-12)33(30,31)29-10-9-17-16(11-29)18(26-28(17)4)21-24-23-20(32-21)14-5-7-15(22)8-6-14/h5-8H,9-11H2,1-4H3

InChI Key

QPYOELPIXGMRAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480707

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.861

Distribution Coefficient, logD

0.861

Water Solubility, LogSw

-2.08

Polar Surface Area

91.712

Acid Dissociation Constant (pKa)

22.32

Base Dissociation Constant (pKb)

1.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L856-0046 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Antifungal Library (16415 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Agro:
  • Agro
Targets:
  • Proteases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L856-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L856-0046?
Check Price and Availability of L856-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L856-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L856-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L856-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L856-0046 available by request