L856-0315 Screening compound: 2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-phenyl-1,3,4-oxadiazole

L856-0315 Screening compound: 2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-phenyl-1,3,4-oxadiazole
L856-0315 Screening compound: 2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-phenyl-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L856-0315
2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-phenyl-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L856-0315

Molecular Formula

C22H18F3N5O3S (C22 H18 F3 N5 O3 S)

Compound Name

2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}-5-phenyl-1,3,4-oxadiazole

IUPAC name

2-{1-methyl-5-[2-(trifluoromethyl)benzenesulfonyl]-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl}-5-phenyl-134-oxadiazole

SMILES

Cn(c(CC1)c2CN1S(c1c(C(F)(F)F)cccc1)(=O)=O)nc2-c1nnc(-c2ccccc2)o1

InChI

InChI=1S/C22H18F3N5O3S/c1-29-17-11-12-30(34(31,32)18-10-6-5-9-16(18)22(23,24)25)13-15(17)19(28-29)21-27-26-20(33-21)14-7-3-2-4-8-14/h2-10H,11-13H2,1H3

InChI Key

MUFOJMOVECMINH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480832

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.404

Distribution Coefficient, logD

3.404

Water Solubility, LogSw

-3.86

Polar Surface Area

76.873

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

-2.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L856-0315 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L856-0315 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L856-0315?
Check Price and Availability of L856-0315, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L856-0315 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L856-0315
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L856-0315
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L856-0315 available by request