L858-0173 Screening compound: N~1~-(2,5-difluorophenyl)-2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]acetamide
Chemical Structure Depiction of ChemDiv screening compound L858-0173
N~1~-(2,5-difluorophenyl)-2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]acetamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L858-0173
Molecular Formula
C19H14F2N4O2S (C19 H14 F2 N4 O2 S)
Compound Name
N~1~-(2,5-difluorophenyl)-2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]acetamide
IUPAC name
N-(25-difluorophenyl)-2-{4-ethyl-6-oxo-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)3911-pentaen-5-yl}acetamide
SMILES
CCC(N(CC(Nc(cc(cc1)F)c1F)=O)C1=O)=Nc2c1sc1ncccc12
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
400.41
Hydrogen Bond Acceptors Count
6.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
3.150
Distribution Coefficient, logD
3.138
Water Solubility, LogSw
-3.16
Polar Surface Area
55.829
Acid Dissociation Constant (pKa)
8.97
Base Dissociation Constant (pKb)
2.59
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
15.80
L858-0173 in Drug Discovery
Included in Screening Libraries
Angiogenesis library (14822 compounds)
Anti-Inflammatory Library (24602 compounds)
Anticancer Library (62698 compounds)
Included in 1.7M Stock Database
- Cancer
- Immune system
- Cancer
References: we are preparing a list of scientific research reports with L858-0173 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)