L858-0186 Screening compound: 2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-(3-methoxyphenyl)acetamide

L858-0186 Screening compound: 2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-(3-methoxyphenyl)acetamide
L858-0186 Screening compound: 2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-(3-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L858-0186
2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-(3-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L858-0186

Molecular Formula

C20H18N4O3S (C20 H18 N4 O3 S)

Compound Name

2-[2-ethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl]-N~1~-(3-methoxyphenyl)acetamide

IUPAC name

2-{4-ethyl-6-oxo-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)3911-pentaen-5-yl}-N-(3-methoxyphenyl)acetamide

SMILES

CCC(N(CC(Nc1cc(OC)ccc1)=O)C1=O)=Nc2c1sc1ncccc12

InChI

InChI=1S/C20H18N4O3S/c1-3-15-23-17-14-8-5-9-21-19(14)28-18(17)20(26)24(15)11-16(25)22-12-6-4-7-13(10-12)27-2/h4-10H,3,11H2,1-2H3,(H,22,25)

InChI Key

SWCHXHGQQHEQJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480937

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.049

Distribution Coefficient, logD

3.049

Water Solubility, LogSw

-3.27

Polar Surface Area

64.071

Acid Dissociation Constant (pKa)

11.76

Base Dissociation Constant (pKb)

2.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

References: we are preparing a list of scientific research reports with L858-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L858-0186?
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What is the minimum amount of L858-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L858-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L858-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L858-0186 available by request