L859-0280 Screening compound: 1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one

L859-0280 Screening compound: 1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one
L859-0280 Screening compound: 1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L859-0280
1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L859-0280

Molecular Formula

C24H16BrClN4O2 (C24 H16 BrClN4 O2)

Compound Name

1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one

IUPAC name

1-[(3-bromophenyl)methyl]-3-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]-7-methyl-14-dihydro-18-naphthyridin-4-one

SMILES

Cc1ccc(C(C(c2nc(-c(cc3)ccc3Cl)no2)=CN2Cc3cccc(Br)c3)=O)c2n1

InChI

InChI=1S/C24H16BrClN4O2/c1-14-5-10-19-21(31)20(24-28-22(29-32-24)16-6-8-18(26)9-7-16)13-30(23(19)27-14)12-15-3-2-4-17(25)11-15/h2-11,13H,12H2,1H3

InChI Key

VMCMFIYTLRKQKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22597875

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

507.77

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.696

Distribution Coefficient, logD

6.696

Water Solubility, LogSw

-6.22

Polar Surface Area

56.673

Acid Dissociation Constant (pKa)

24.92

Base Dissociation Constant (pKb)

0.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

L859-0280 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L859-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L859-0280?
Check Price and Availability of L859-0280, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L859-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L859-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L859-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L859-0280 available by request