L859-0431 Screening compound: N-(2,5-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}acetamide

L859-0431 Screening compound: N-(2,5-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}acetamide
L859-0431 Screening compound: N-(2,5-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L859-0431
N-(2,5-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L859-0431

Molecular Formula

C27H22FN5O3 (C27 H22 FN5 O3)

Compound Name

N-(2,5-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}acetamide

IUPAC name

N-(25-dimethylphenyl)-2-{3-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-7-methyl-4-oxo-14-dihydro-18-naphthyridin-1-yl}acetamide

SMILES

Cc1cc(NC(CN(C=C2c3nc(-c4cccc(F)c4)no3)c(nc(C)cc3)c3C2=O)=O)c(C)cc1

InChI

InChI=1S/C27H22FN5O3/c1-15-7-8-16(2)22(11-15)30-23(34)14-33-13-21(24(35)20-10-9-17(3)29-26(20)33)27-31-25(32-36-27)18-5-4-6-19(28)12-18/h4-13H,14H2,1-3H3,(H,30,34)

InChI Key

VPPKPRAJQLFRMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27481329

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.316

Distribution Coefficient, logD

5.316

Water Solubility, LogSw

-5.31

Polar Surface Area

79.125

Acid Dissociation Constant (pKa)

12.74

Base Dissociation Constant (pKb)

1.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L859-0431 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L859-0431 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L859-0431?
Check Price and Availability of L859-0431, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L859-0431 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L859-0431
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L859-0431
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L859-0431 available by request