L859-1078 Screening compound: 2-{7-methyl-3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide

L859-1078 Screening compound: 2-{7-methyl-3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide
L859-1078 Screening compound: 2-{7-methyl-3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L859-1078
2-{7-methyl-3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L859-1078

Molecular Formula

C25H21N5O3S (C25 H21 N5 O3 S)

Compound Name

2-{7-methyl-3-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide

IUPAC name

2-{7-methyl-3-[3-(3-methylphenyl)-124-oxadiazol-5-yl]-4-oxo-14-dihydro-18-naphthyridin-1-yl}-N-[(thiophen-2-yl)methyl]acetamide

SMILES

Cc1cccc(-c2noc(C3=CN(CC(NCc4cccs4)=O)c4nc(C)ccc4C3=O)n2)c1

InChI

InChI=1S/C25H21N5O3S/c1-15-5-3-6-17(11-15)23-28-25(33-29-23)20-13-30(14-21(31)26-12-18-7-4-10-34-18)24-19(22(20)32)9-8-16(2)27-24/h3-11,13H,12,14H2,1-2H3,(H,26,31)

InChI Key

SOYQCZFLIQUCEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15135213

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.075

Distribution Coefficient, logD

5.075

Water Solubility, LogSw

-4.80

Polar Surface Area

82.163

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

L859-1078 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L859-1078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L859-1078?
Check Price and Availability of L859-1078, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L859-1078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L859-1078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L859-1078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L859-1078 available by request