L860-0623 Screening compound: 3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide

L860-0623 Screening compound: 3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
L860-0623 Screening compound: 3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L860-0623
3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L860-0623

Molecular Formula

C24H22ClN5O2S (C24 H22 ClN5 O2 S)

Compound Name

3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide

IUPAC name

3-({[(2-chloro-4-methylphenyl)carbamoyl]methyl}sulfanyl)-N-[(4-methylphenyl)methyl]-[124]triazolo[43-a]pyridine-6-carboxamide

SMILES

Cc1ccc(CNC(c2cn3c(SCC(Nc(ccc(C)c4)c4Cl)=O)nnc3cc2)=O)cc1

InChI

InChI=1S/C24H22ClN5O2S/c1-15-3-6-17(7-4-15)12-26-23(32)18-8-10-21-28-29-24(30(21)13-18)33-14-22(31)27-20-9-5-16(2)11-19(20)25/h3-11,13H,12,14H2,1-2H3,(H,26,32)(H,27,31)

InChI Key

ZPQYCEWKYDTYKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27481574

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.99

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.173

Distribution Coefficient, logD

4.173

Water Solubility, LogSw

-4.38

Polar Surface Area

68.917

Acid Dissociation Constant (pKa)

10.82

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L860-0623 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L860-0623 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L860-0623?
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What is the minimum amount of L860-0623 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L860-0623
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L860-0623
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L860-0623 available by request