L863-0197 Screening compound: 2-[6-(4-methylphenyl)-2-(methylsulfanyl)-5,7-dioxo-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]-N-(2,4,6-trimethylphenyl)acetamide

L863-0197 Screening compound: 2-[6-(4-methylphenyl)-2-(methylsulfanyl)-5,7-dioxo-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]-N-(2,4,6-trimethylphenyl)acetamide
L863-0197 Screening compound: 2-[6-(4-methylphenyl)-2-(methylsulfanyl)-5,7-dioxo-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]-N-(2,4,6-trimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L863-0197
2-[6-(4-methylphenyl)-2-(methylsulfanyl)-5,7-dioxo-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]-N-(2,4,6-trimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L863-0197

Molecular Formula

C24H24N4O3S2 (C24 H24 N4 O3 S2)

Compound Name

2-[6-(4-methylphenyl)-2-(methylsulfanyl)-5,7-dioxo-4H,5H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-4-yl]-N-(2,4,6-trimethylphenyl)acetamide

IUPAC name

2-[6-(4-methylphenyl)-2-(methylsulfanyl)-57-dioxo-4H5H6H7H-[13]thiazolo[45-d]pyrimidin-4-yl]-N-(246-trimethylphenyl)acetamide

SMILES

Cc(cc1)ccc1N(C(c1c(N2CC(Nc3c(C)cc(C)cc3C)=O)nc(SC)s1)=O)C2=O

InChI

InChI=1S/C24H24N4O3S2/c1-13-6-8-17(9-7-13)28-22(30)20-21(26-23(32-5)33-20)27(24(28)31)12-18(29)25-19-15(3)10-14(2)11-16(19)4/h6-11H,12H2,1-5H3,(H,25,29)

InChI Key

MSXANUVZNVWHFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482151

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.61

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.898

Distribution Coefficient, logD

4.898

Water Solubility, LogSw

-4.49

Polar Surface Area

63.059

Acid Dissociation Constant (pKa)

12.39

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L863-0197 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L863-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L863-0197?
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What is the minimum amount of L863-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L863-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L863-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L863-0197 available by request