L865-0132 Screening compound: 2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

L865-0132 Screening compound: 2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
L865-0132 Screening compound: 2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L865-0132
2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L865-0132

Molecular Formula

C21H30N6O2S (C21 H30 N6 O2 S)

Compound Name

2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

2-[4-(4-cyclohexylpiperazine-1-carbonyl)piperidin-1-yl]-6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

O=C(C(CC1)CCN1c1nc(N=CNC2=O)c2s1)N(CC1)CCN1C1CCCCC1

InChI

InChI=1S/C21H30N6O2S/c28-19-17-18(22-14-23-19)24-21(30-17)27-8-6-15(7-9-27)20(29)26-12-10-25(11-13-26)16-4-2-1-3-5-16/h14-16H,1-13H2,(H,22,23,28)

InChI Key

JISMQIACQDLYPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.053

Distribution Coefficient, logD

1.640

Water Solubility, LogSw

-2.46

Polar Surface Area

69.525

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

7.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

71.43

L865-0132 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L865-0132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L865-0132?
Check Price and Availability of L865-0132, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L865-0132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L865-0132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L865-0132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L865-0132 available by request