L865-1773 Screening compound: 1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide

L865-1773 Screening compound: 1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide
L865-1773 Screening compound: 1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L865-1773
1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L865-1773

Molecular Formula

C22H25ClN6O3S (C22 H25 ClN6 O3 S)

Compound Name

1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide

IUPAC name

1-(6-{[(3-chloro-2-methylphenyl)carbamoyl]methyl}-7-oxo-6H7H-[13]thiazolo[45-d]pyrimidin-2-yl)-N-ethylpiperidine-4-carboxamide

SMILES

CCNC(C(CC1)CCN1c1nc(N=CN(CC(Nc2cccc(Cl)c2C)=O)C2=O)c2s1)=O

InChI

InChI=1S/C22H25ClN6O3S/c1-3-24-20(31)14-7-9-28(10-8-14)22-27-19-18(33-22)21(32)29(12-25-19)11-17(30)26-16-6-4-5-15(23)13(16)2/h4-6,12,14H,3,7-11H2,1-2H3,(H,24,31)(H,26,30)

InChI Key

FTUYLQQPCUHHGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482600

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.849

Distribution Coefficient, logD

2.849

Water Solubility, LogSw

-3.32

Polar Surface Area

86.950

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

5.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L865-1773 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L865-1773 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L865-1773?
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What is the minimum amount of L865-1773 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L865-1773
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L865-1773
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L865-1773 available by request