L865-2242 Screening compound: N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-6-yl}acetamide

L865-2242 Screening compound: N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-6-yl}acetamide
L865-2242 Screening compound: N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-6-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L865-2242
N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-6-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L865-2242

Molecular Formula

C24H27FN6O3S (C24 H27 FN6 O3 S)

Compound Name

N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-6-yl}acetamide

IUPAC name

N-(2-fluorophenyl)-2-{7-oxo-2-[4-(piperidine-1-carbonyl)piperidin-1-yl]-6H7H-[13]thiazolo[45-d]pyrimidin-6-yl}acetamide

SMILES

O=C(CN(C=Nc1c2sc(N(CC3)CCC3C(N3CCCCC3)=O)n1)C2=O)Nc(cccc1)c1F

InChI

InChI=1S/C24H27FN6O3S/c25-17-6-2-3-7-18(17)27-19(32)14-31-15-26-21-20(23(31)34)35-24(28-21)30-12-8-16(9-13-30)22(33)29-10-4-1-5-11-29/h2-3,6-7,15-16H,1,4-5,8-14H2,(H,27,32)

InChI Key

KDWWPGAJIKXZTJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482710

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.736

Distribution Coefficient, logD

2.736

Water Solubility, LogSw

-3.03

Polar Surface Area

79.287

Acid Dissociation Constant (pKa)

11.03

Base Dissociation Constant (pKb)

0.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

L865-2242 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with L865-2242 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L865-2242?
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What is the minimum amount of L865-2242 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L865-2242
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L865-2242
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L865-2242 available by request