L866-0167 Screening compound: ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-1,2-dihydroquinoxalin-1-yl}acetamido)benzoate

L866-0167 Screening compound: ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-1,2-dihydroquinoxalin-1-yl}acetamido)benzoate
L866-0167 Screening compound: ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-1,2-dihydroquinoxalin-1-yl}acetamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L866-0167
ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-1,2-dihydroquinoxalin-1-yl}acetamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L866-0167

Molecular Formula

C24H26N4O5 (C24 H26 N4 O5)

Compound Name

ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-1,2-dihydroquinoxalin-1-yl}acetamido)benzoate

IUPAC name

ethyl 3-(2-{3-[2-(ethylcarbamoyl)ethyl]-2-oxo-12-dihydroquinoxalin-1-yl}acetamido)benzoate

SMILES

CCNC(CCC1=Nc(cccc2)c2N(CC(Nc2cc(C(OCC)=O)ccc2)=O)C1=O)=O

InChI

InChI=1S/C24H26N4O5/c1-3-25-21(29)13-12-19-23(31)28(20-11-6-5-10-18(20)27-19)15-22(30)26-17-9-7-8-16(14-17)24(32)33-4-2/h5-11,14H,3-4,12-13,15H2,1-2H3,(H,25,29)(H,26,30)

InChI Key

NVWCNUORBLSIRM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27482757

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.375

Distribution Coefficient, logD

2.375

Water Solubility, LogSw

-2.92

Polar Surface Area

91.354

Acid Dissociation Constant (pKa)

12.11

Base Dissociation Constant (pKb)

1.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L866-0167 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with L866-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L866-0167?
Check Price and Availability of L866-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L866-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L866-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L866-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L866-0167 available by request