L871-0367 Screening compound: N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide

L871-0367 Screening compound: N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide
L871-0367 Screening compound: N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L871-0367
N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L871-0367

Molecular Formula

C27H24ClFN4O3S (C27 H24 ClFN4 O3 S)

Compound Name

N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide

IUPAC name

N-{[5-(2-chlorobenzenesulfonyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]methyl}-2-fluoro-N-phenylbenzamide

SMILES

Cn1nc(CN(C(c(cccc2)c2F)=O)c2ccccc2)c(C2)c1CCN2S(c(cccc1)c1Cl)(=O)=O

InChI

InChI=1S/C27H24ClFN4O3S/c1-31-25-15-16-32(37(35,36)26-14-8-6-12-22(26)28)17-21(25)24(30-31)18-33(19-9-3-2-4-10-19)27(34)20-11-5-7-13-23(20)29/h2-14H,15-18H2,1H3

InChI Key

WHOBBWBTVXHMLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27483240

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

539.03

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.156

Distribution Coefficient, logD

4.156

Water Solubility, LogSw

-4.52

Polar Surface Area

62.475

Acid Dissociation Constant (pKa)

22.23

Base Dissociation Constant (pKb)

-1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

L871-0367 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L871-0367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L871-0367?
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What is the minimum amount of L871-0367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L871-0367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L871-0367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L871-0367 available by request