L878-2176 Screening compound: ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-1,2-dihydroquinazolin-4-yl)piperidine-4-carboxylate

L878-2176 Screening compound: ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-1,2-dihydroquinazolin-4-yl)piperidine-4-carboxylate
L878-2176 Screening compound: ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-1,2-dihydroquinazolin-4-yl)piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L878-2176
ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-1,2-dihydroquinazolin-4-yl)piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L878-2176

Molecular Formula

C26H28N4O5 (C26 H28 N4 O5)

Compound Name

ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-1,2-dihydroquinazolin-4-yl)piperidine-4-carboxylate

IUPAC name

ethyl 1-(1-{[(3-acetylphenyl)carbamoyl]methyl}-2-oxo-12-dihydroquinazolin-4-yl)piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(c(cccc1)c1N1CC(Nc2cc(C(C)=O)ccc2)=O)=NC1=O)=O

InChI

InChI=1S/C26H28N4O5/c1-3-35-25(33)18-11-13-29(14-12-18)24-21-9-4-5-10-22(21)30(26(34)28-24)16-23(32)27-20-8-6-7-19(15-20)17(2)31/h4-10,15,18H,3,11-14,16H2,1-2H3,(H,27,32)

InChI Key

FVTGDHYTCMAIFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27483773

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.903

Distribution Coefficient, logD

2.902

Water Solubility, LogSw

-3.47

Polar Surface Area

83.870

Acid Dissociation Constant (pKa)

11.06

Base Dissociation Constant (pKb)

4.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L878-2176 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with L878-2176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L878-2176?
Check Price and Availability of L878-2176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L878-2176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L878-2176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L878-2176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L878-2176 available by request