L878-2217 Screening compound: ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-1,2-dihydroquinazolin-4-yl]piperidine-4-carboxylate

L878-2217 Screening compound: ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-1,2-dihydroquinazolin-4-yl]piperidine-4-carboxylate
L878-2217 Screening compound: ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-1,2-dihydroquinazolin-4-yl]piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L878-2217
ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-1,2-dihydroquinazolin-4-yl]piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L878-2217

Molecular Formula

C25H27ClN4O4 (C25 H27 ClN4 O4)

Compound Name

ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-1,2-dihydroquinazolin-4-yl]piperidine-4-carboxylate

IUPAC name

ethyl 1-[1-({[(4-chlorophenyl)methyl]carbamoyl}methyl)-2-oxo-12-dihydroquinazolin-4-yl]piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(c(cccc1)c1N1CC(NCc(cc2)ccc2Cl)=O)=NC1=O)=O

InChI

InChI=1S/C25H27ClN4O4/c1-2-34-24(32)18-11-13-29(14-12-18)23-20-5-3-4-6-21(20)30(25(33)28-23)16-22(31)27-15-17-7-9-19(26)10-8-17/h3-10,18H,2,11-16H2,1H3,(H,27,31)

InChI Key

CJPFSLFEGKLLGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27483790

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.97

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.335

Distribution Coefficient, logD

3.324

Water Solubility, LogSw

-3.90

Polar Surface Area

71.365

Acid Dissociation Constant (pKa)

12.85

Base Dissociation Constant (pKb)

5.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

L878-2217 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L878-2217 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L878-2217?
Check Price and Availability of L878-2217, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L878-2217 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L878-2217
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L878-2217
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L878-2217 available by request