L888-0215 Screening compound: 3-[5-(2,3-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole

L888-0215 Screening compound: 3-[5-(2,3-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole
L888-0215 Screening compound: 3-[5-(2,3-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L888-0215
3-[5-(2,3-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L888-0215

Molecular Formula

C20H24N6O2S2 (C20 H24 N6 O2 S2)

Compound Name

3-[5-(2,3-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole

IUPAC name

3-[5-(23-dihydro-1H-indene-5-sulfonyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]-4-methyl-5-(methylsulfanyl)-4H-124-triazole

SMILES

Cn1c(SC)nnc1-c1nn(C)c(CC2)c1CN2S(c1cc(CCC2)c2cc1)(=O)=O

InChI

InChI=1S/C20H24N6O2S2/c1-24-19(21-22-20(24)29-3)18-16-12-26(10-9-17(16)25(2)23-18)30(27,28)15-8-7-13-5-4-6-14(13)11-15/h7-8,11H,4-6,9-10,12H2,1-3H3

InChI Key

BZSQBRPGRWRLDR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15136298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.478

Distribution Coefficient, logD

2.474

Water Solubility, LogSw

-2.74

Polar Surface Area

71.999

Acid Dissociation Constant (pKa)

20.77

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

L888-0215 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L888-0215 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L888-0215?
Check Price and Availability of L888-0215, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L888-0215 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L888-0215
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L888-0215
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L888-0215 available by request