L892-0057 Screening compound: N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide

L892-0057 Screening compound: N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide
L892-0057 Screening compound: N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L892-0057
N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L892-0057

Molecular Formula

C25H23N3O2 (C25 H23 N3 O2)

Compound Name

N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide

IUPAC name

N-[2-methyl-4-(2-methyl-4-oxo-34-dihydroquinazolin-3-yl)phenyl]-3-phenylpropanamide

SMILES

Cc(cc(cc1)N(C(C)=Nc2c3cccc2)C3=O)c1NC(CCc1ccccc1)=O

InChI

InChI=1S/C25H23N3O2/c1-17-16-20(28-18(2)26-23-11-7-6-10-21(23)25(28)30)13-14-22(17)27-24(29)15-12-19-8-4-3-5-9-19/h3-11,13-14,16H,12,15H2,1-2H3,(H,27,29)

InChI Key

QLIVWZPXZYBBCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15136313

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.479

Distribution Coefficient, logD

3.329

Water Solubility, LogSw

-3.84

Polar Surface Area

45.954

Acid Dissociation Constant (pKa)

11.63

Base Dissociation Constant (pKb)

7.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

L892-0057 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L892-0057 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L892-0057?
Check Price and Availability of L892-0057, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L892-0057 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L892-0057
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L892-0057
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L892-0057 available by request