L892-0114 Screening compound: 4-chloro-2-methoxy-N~1~-{2-methyl-4-[2-methyl-4-oxo-3(4H)-quinazolinyl]phenyl}benzamide

L892-0114 Screening compound: 4-chloro-2-methoxy-N~1~-{2-methyl-4-[2-methyl-4-oxo-3(4H)-quinazolinyl]phenyl}benzamide
L892-0114 Screening compound: 4-chloro-2-methoxy-N~1~-{2-methyl-4-[2-methyl-4-oxo-3(4H)-quinazolinyl]phenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L892-0114
4-chloro-2-methoxy-N~1~-{2-methyl-4-[2-methyl-4-oxo-3(4H)-quinazolinyl]phenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L892-0114

Molecular Formula

C24H20ClN3O3 (C24 H20 ClN3 O3)

Compound Name

4-chloro-2-methoxy-N~1~-{2-methyl-4-[2-methyl-4-oxo-3(4H)-quinazolinyl]phenyl}benzamide

IUPAC name

4-chloro-2-methoxy-N-[2-methyl-4-(2-methyl-4-oxo-34-dihydroquinazolin-3-yl)phenyl]benzamide

SMILES

Cc(cc(cc1)N(C(C)=Nc2c3cccc2)C3=O)c1NC(c(ccc(Cl)c1)c1OC)=O

InChI

InChI=1S/C24H20ClN3O3/c1-14-12-17(28-15(2)26-21-7-5-4-6-18(21)24(28)30)9-11-20(14)27-23(29)19-10-8-16(25)13-22(19)31-3/h4-13H,1-3H3,(H,27,29)

InChI Key

IIBCXVISFZSXHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27484460

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.89

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.238

Distribution Coefficient, logD

4.056

Water Solubility, LogSw

-4.55

Polar Surface Area

53.798

Acid Dissociation Constant (pKa)

8.51

Base Dissociation Constant (pKb)

7.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

L892-0114 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L892-0114 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L892-0114?
Check Price and Availability of L892-0114, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L892-0114 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L892-0114
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L892-0114
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L892-0114 available by request