L892-0189 Screening compound: 3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzamide

L892-0189 Screening compound: 3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzamide
L892-0189 Screening compound: 3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L892-0189
3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L892-0189

Molecular Formula

C23H18BrN3O2 (C23 H18 BrN3 O2)

Compound Name

3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzamide

IUPAC name

3-bromo-4-methyl-N-[4-(2-methyl-4-oxo-34-dihydroquinazolin-3-yl)phenyl]benzamide

SMILES

Cc(ccc(C(Nc(cc1)ccc1N(C(C)=Nc1c2cccc1)C2=O)=O)c1)c1Br

InChI

InChI=1S/C23H18BrN3O2/c1-14-7-8-16(13-20(14)24)22(28)26-17-9-11-18(12-10-17)27-15(2)25-21-6-4-3-5-19(21)23(27)29/h3-13H,1-2H3,(H,26,28)

InChI Key

KUSQHIOBBRZOLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27484467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.32

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.171

Distribution Coefficient, logD

4.133

Water Solubility, LogSw

-4.30

Polar Surface Area

46.865

Acid Dissociation Constant (pKa)

9.97

Base Dissociation Constant (pKb)

6.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

L892-0189 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L892-0189 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L892-0189?
Check Price and Availability of L892-0189, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L892-0189 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L892-0189
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L892-0189
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L892-0189 available by request