L892-0269 Screening compound: N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-5-phenyl-1,3-oxazole-4-carboxamide

L892-0269 Screening compound: N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-5-phenyl-1,3-oxazole-4-carboxamide
L892-0269 Screening compound: N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-5-phenyl-1,3-oxazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L892-0269
N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-5-phenyl-1,3-oxazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L892-0269

Molecular Formula

C25H18N4O3 (C25 H18 N4 O3)

Compound Name

N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-5-phenyl-1,3-oxazole-4-carboxamide

IUPAC name

N-[4-(2-methyl-4-oxo-34-dihydroquinazolin-3-yl)phenyl]-5-phenyl-13-oxazole-4-carboxamide

SMILES

CC(N1c(cc2)ccc2NC(c2c(-c3ccccc3)ocn2)=O)=Nc(cccc2)c2C1=O

InChI

InChI=1S/C25H18N4O3/c1-16-27-21-10-6-5-9-20(21)25(31)29(16)19-13-11-18(12-14-19)28-24(30)22-23(32-15-26-22)17-7-3-2-4-8-17/h2-15H,1H3,(H,28,30)

InChI Key

VKFXJRWDIAZKBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15136337

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.252

Distribution Coefficient, logD

3.216

Water Solubility, LogSw

-3.89

Polar Surface Area

65.701

Acid Dissociation Constant (pKa)

12.74

Base Dissociation Constant (pKb)

6.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.00

L892-0269 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L892-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L892-0269?
Check Price and Availability of L892-0269, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L892-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L892-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L892-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L892-0269 available by request