L893-0477 Screening compound: 2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine

L893-0477 Screening compound: 2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine
L893-0477 Screening compound: 2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L893-0477
2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L893-0477

Molecular Formula

C27H30ClN5O2 (C27 H30 ClN5 O2)

Compound Name

2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine

IUPAC name

2-{4-[4-(4-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-3-(2-methylphenoxy)pyrazine

SMILES

Cc(cccc1)c1Oc1nccnc1N(CC1)CCC1C(N(CC1)CCN1c(cc1)ccc1Cl)=O

InChI

InChI=1S/C27H30ClN5O2/c1-20-4-2-3-5-24(20)35-26-25(29-12-13-30-26)32-14-10-21(11-15-32)27(34)33-18-16-31(17-19-33)23-8-6-22(28)7-9-23/h2-9,12-13,21H,10-11,14-19H2,1H3

InChI Key

XXSXKOHAUUHRFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15136453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.02

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.223

Distribution Coefficient, logD

5.223

Water Solubility, LogSw

-5.68

Polar Surface Area

49.220

Acid Dissociation Constant (pKa)

22.96

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

L893-0477 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L893-0477 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L893-0477?
Check Price and Availability of L893-0477, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L893-0477 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L893-0477
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L893-0477
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L893-0477 available by request