L895-0214 Screening compound: 1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide

L895-0214 Screening compound: 1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide
L895-0214 Screening compound: 1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L895-0214
1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L895-0214

Molecular Formula

C22H23N5OS (C22 H23 N5 OS)

Compound Name

1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide

IUPAC name

1-[3-(phenylsulfanyl)pyrazin-2-yl]-N-[(pyridin-2-yl)methyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1nccnc1Sc1ccccc1)NCc1ncccc1

InChI

InChI=1S/C22H23N5OS/c28-21(26-15-18-8-4-5-11-23-18)17-7-6-14-27(16-17)20-22(25-13-12-24-20)29-19-9-2-1-3-10-19/h1-5,8-13,17H,6-7,14-16H2,(H,26,28)/t17-/m0/s1

InChI Key

UPSGXYDLITUSKL-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD15136623

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.814

Distribution Coefficient, logD

2.814

Water Solubility, LogSw

-3.18

Polar Surface Area

55.469

Acid Dissociation Constant (pKa)

12.16

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

L895-0214 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L895-0214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L895-0214?
Check Price and Availability of L895-0214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L895-0214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L895-0214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L895-0214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L895-0214 available by request