L895-0284 Screening compound: morpholino{1-[3-(phenylsulfanyl)-2-pyrazinyl]-3-piperidyl}methanone

L895-0284 Screening compound: morpholino{1-[3-(phenylsulfanyl)-2-pyrazinyl]-3-piperidyl}methanone
L895-0284 Screening compound: morpholino{1-[3-(phenylsulfanyl)-2-pyrazinyl]-3-piperidyl}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L895-0284
morpholino{1-[3-(phenylsulfanyl)-2-pyrazinyl]-3-piperidyl}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L895-0284

Molecular Formula

C20H24N4O2S (C20 H24 N4 O2 S)

Compound Name

morpholino{1-[3-(phenylsulfanyl)-2-pyrazinyl]-3-piperidyl}methanone

IUPAC name

4-{1-[3-(phenylsulfanyl)pyrazin-2-yl]piperidine-3-carbonyl}morpholine

SMILES

O=C(C(CCC1)CN1c1nccnc1Sc1ccccc1)N1CCOCC1

InChI

InChI=1S/C20H24N4O2S/c25-20(23-11-13-26-14-12-23)16-5-4-10-24(15-16)18-19(22-9-8-21-18)27-17-6-2-1-3-7-17/h1-3,6-9,16H,4-5,10-15H2/t16-/m0/s1

InChI Key

YSQPLJVSCYWEMB-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15136649

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.424

Distribution Coefficient, logD

2.424

Water Solubility, LogSw

-2.44

Polar Surface Area

46.070

Acid Dissociation Constant (pKa)

22.75

Base Dissociation Constant (pKb)

0.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.00

L895-0284 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L895-0284 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L895-0284?
Check Price and Availability of L895-0284, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L895-0284 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L895-0284
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L895-0284
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L895-0284 available by request