L899-0257 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one

L899-0257 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one
L899-0257 Screening compound: 1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L899-0257
1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L899-0257

Molecular Formula

C22H21ClN4O2S (C22 H21 ClN4 O2 S)

Compound Name

1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one

IUPAC name

1-[4-(4-chlorophenyl)piperazin-1-yl]-2-[(3-phenoxypyrazin-2-yl)sulfanyl]ethan-1-one

SMILES

O=C(CSc1nccnc1Oc1ccccc1)N(CC1)CCN1c(cc1)ccc1Cl

InChI

InChI=1S/C22H21ClN4O2S/c23-17-6-8-18(9-7-17)26-12-14-27(15-13-26)20(28)16-30-22-21(24-10-11-25-22)29-19-4-2-1-3-5-19/h1-11H,12-16H2

InChI Key

NOHWZZDOPGOUDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27485287

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.95

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.499

Distribution Coefficient, logD

4.499

Water Solubility, LogSw

-4.92

Polar Surface Area

45.352

Acid Dissociation Constant (pKa)

21.51

Base Dissociation Constant (pKb)

5.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L899-0257 in Drug Discovery

Included in Screening Libraries

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L899-0257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L899-0257?
Check Price and Availability of L899-0257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L899-0257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L899-0257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L899-0257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L899-0257 available by request