L899-0735 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one

L899-0735 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one
L899-0735 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L899-0735
1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L899-0735

Molecular Formula

C24H25ClN4O2S (C24 H25 ClN4 O2 S)

Compound Name

1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one

IUPAC name

1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-{[3-(2-methylphenoxy)pyrazin-2-yl]sulfanyl}ethan-1-one

SMILES

Cc(ccc(Cl)c1)c1N(CC1)CCN1C(CSc1nccnc1Oc1c(C)cccc1)=O

InChI

InChI=1S/C24H25ClN4O2S/c1-17-7-8-19(25)15-20(17)28-11-13-29(14-12-28)22(30)16-32-24-23(26-9-10-27-24)31-21-6-4-3-5-18(21)2/h3-10,15H,11-14,16H2,1-2H3

InChI Key

KCVSRKLAOQDPCW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27485350

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.01

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.236

Distribution Coefficient, logD

5.236

Water Solubility, LogSw

-5.63

Polar Surface Area

45.138

Acid Dissociation Constant (pKa)

21.51

Base Dissociation Constant (pKb)

2.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L899-0735 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with L899-0735 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L899-0735?
Check Price and Availability of L899-0735, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L899-0735 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L899-0735
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L899-0735
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L899-0735 available by request