L901-0268 Screening compound: 2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine

L901-0268 Screening compound: 2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine
L901-0268 Screening compound: 2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L901-0268
2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L901-0268

Molecular Formula

C26H23N5O2S (C26 H23 N5 O2 S)

Compound Name

2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine

IUPAC name

2-phenoxy-3-({2-[4-(pyridin-2-yl)piperazine-1-carbonyl]phenyl}sulfanyl)pyrazine

SMILES

O=C(c(cccc1)c1Sc1nccnc1Oc1ccccc1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C26H23N5O2S/c32-26(31-18-16-30(17-19-31)23-12-6-7-13-27-23)21-10-4-5-11-22(21)34-25-24(28-14-15-29-25)33-20-8-2-1-3-9-20/h1-15H,16-19H2

InChI Key

PWYUMMLQEHPMMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27485571

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.848

Distribution Coefficient, logD

4.839

Water Solubility, LogSw

-4.83

Polar Surface Area

54.119

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

L901-0268 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L901-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L901-0268?
Check Price and Availability of L901-0268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L901-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L901-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L901-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L901-0268 available by request